Target:BCA3
Gene Name:AKIP1
Protein Name:A-kinase-interacting protein 1
Human Gene Id:56672
Human Swiss Prot No:Q9NQ31
Mouse Swiss Prot No:Q9JJR5
Immunogen:The antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160
Specificity:BCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:AKIP1;BCA3;C11orf17;A-kinase-interacting protein 1;Breast cancer-associated gene 3 protein;PKA-interacting protein;Proline-rich protein BCA3
Observed Band(KD):26kD
Background: This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
Function:subcellular location:Locates to punctate spots.,subunit:Interacts with PRKACA.,tissue specificity:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.,
Subcellular Location:Nucleus . Locates to punctate spots.
Expression:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.