Target：BATF3

Fields：PD-L1 expression and PD-1 checkpoint pathway in cancer

Gene Name：BATF3

Protein Name：Basic leucine zipper transcriptional factor ATF-like 3

Human Gene Id：55509

Human Swiss Prot No：Q9NR55

Mouse Gene Id：381319

Mouse Swiss Prot No：Q9D275

Rat Swiss Prot No：P97876

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human BATF3. AA range:1-50

Specificity：BATF3 Polyclonal Antibody detects endogenous levels of BATF3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：BATF3;SNFT;Basic leucine zipper transcriptional factor ATF-like 3;B-ATF-3;21 kDa small nuclear factor isolated from T-cells;Jun dimerization protein p21SNFT

Observed Band(KD)：15kD

Background： This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009],

Function：function:Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12-O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Interacts with JUN.,

Subcellular Location：Nucleus .

Expression： Lung,