Target：PMS2/PMS2CL

Gene Name：PMS2/PMS2CL

Protein Name：Mismatch repair endonuclease PMS2/Protein PMS2CL

Human Gene Id：5395

Human Swiss Prot No：Q68D20/P54278

Immunogen：The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174

Specificity：PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PMS2CL;Protein PMS2CL;PMS2-C terminal-like protein;PMS2;PMSL2;Mismatch repair endonuclease PMS2;DNA mismatch repair protein PMS2;PMS1 protein homolog 2

Molecular Weight(Da)：21kD

Background：caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,

Function：caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,

Subcellular Location：mismatch repair complex,

Expression： Fetal brain,Testis,