Target：Eps8L1

Gene Name：EPS8L1

Protein Name：Epidermal growth factor receptor kinase substrate 8-like protein 1

Human Gene Id：54869

Human Swiss Prot No：Q8TE68

Mouse Gene Id：67425

Mouse Swiss Prot No：Q8R5F8

Immunogen：The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460

Specificity：Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：EPS8L1;DRC3;EPS8R1;PP10566;Epidermal growth factor receptor kinase substrate 8-like protein 1;EPS8-like protein 1;Epidermal growth factor receptor pathway substrate 8-related protein 1;EPS8-related protein 1

Observed Band(KD)：80kD

Background： This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Function：function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta.,

Subcellular Location：Cytoplasm .

Expression：Detected in placenta.