Target：ATP4B

Fields：Oxidative phosphorylation;Metabolic pathways;Collecting duct acid secretion;Gastric acid secretion

Gene Name：ATP4B

Protein Name：Potassium-transporting ATPase subunit beta (Gastric H(+)/K(+) ATPase subunit beta) (Proton pump beta chain)

Human Gene Id：496

Human Swiss Prot No：P51164

Mouse Swiss Prot No：P50992

Rat Swiss Prot No：P18598

Immunogen：Synthesized peptide derived from human protein . at AA range: 160-240

Specificity：ATP4B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：32kD

Background： The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the X(+)/potassium ATPases subunit beta family.,subunit:Composed of two subunits: alpha (catalytic) and beta.,

Subcellular Location：Apical cell membrane ; Single-pass type II membrane protein . Cell membrane ; Single-pass type II membrane protein . Localized in the apical canalicular membrane of parietal cells. .

Expression： Colon,Liver,