Target：GIMAP4

Gene Name：GIMAP4

Protein Name：GTPase IMAP family member 4

Human Gene Id：55303

Human Swiss Prot No：Q9NUV9

Mouse Swiss Prot No：Q99JY3

Immunogen：The antiserum was produced against synthesized peptide derived from human GIMAP4. AA range:131-180

Specificity：GIMAP4 Polyclonal Antibody detects endogenous levels of GIMAP4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GIMAP4;IAN1;IMAP4;MSTP062;GTPase IMAP family member 4;Immunity-associated nucleotide 1 protein;IAN-1;hIAN1;Immunity-associated protein 4

Observed Band(KD)：38kD

Background： This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008],

Function：function:Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.,similarity:Belongs to the IAN GTP-binding protein family.,tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.,

Subcellular Location：Cytoplasm, cytosol .

Expression：Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.