Target：EMR1

Gene Name：EMR1

Protein Name：EGF-like module-containing mucin-like hormone receptor-like 1

Human Gene Id：2015

Human Swiss Prot No：Q14246

Mouse Swiss Prot No：Q61549

Immunogen：The antiserum was produced against synthesized peptide derived from human EMR1. AA range:818-867

Specificity：EMR1 Polyclonal Antibody detects endogenous levels of EMR1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：EMR1;TM7LN3;EGF-like module-containing mucin-like hormone receptor-like 1;EGF-like module receptor 1;EMR1 hormone receptor

Observed Band(KD)：98kD

Background： This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Function：alternative products:Comment=Additional isoforms seem to exist,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 6 EGF-like domains.,tissue specificity:Wide expression; increased levels in peripheral blood mononuclear cells.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Expression is restricted to eosinophils.