Target：ELOVL5
Fields：Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Fatty acid metabolism
Gene Name：ELOVL5
Protein Name：Elongation of very long chain fatty acids protein 5
Human Gene Id：60481
Human Swiss Prot No：Q9NYP7
Mouse Swiss Prot No：Q8BHI7
Immunogen：The antiserum was produced against synthesized peptide derived from human ELOVL5. AA range:250-299
Specificity：ELOVL5 Polyclonal Antibody detects endogenous levels of ELOVL5 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：ELOVL5;ELOVL2;Elongation of very long chain fatty acids protein 5;3-keto acyl-CoA synthase ELOVL5;ELOVL fatty acid elongase 5;ELOVL FA elongase 5;Fatty acid elongase 1;hELO1
Observed Band(KD)：28kD
Background： This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
Function：function:May be involved in the elongation of long-chain polyunsaturated fatty acids (PUFAs).,similarity:Belongs to the ELO family.,tissue specificity:Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.,
Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell projection, dendrite . In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree. .
Expression：Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.
