Target：GDI-2

Gene Name：GDI2

Protein Name：Rab GDP dissociation inhibitor beta

Human Gene Id：2665

Human Swiss Prot No：P50395

Mouse Gene Id：14569

Mouse Swiss Prot No：Q61598

Rat Gene Id：29662

Rat Swiss Prot No：P50399

Immunogen：Synthesized peptide derived from the C-terminal region of human GDI-2.

Specificity：GDI-2 Polyclonal Antibody detects endogenous levels of GDI-2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GDI2;RABGDIB;Rab GDP dissociation inhibitor beta;Rab GDI beta;Guanosine diphosphate dissociation inhibitor 2;GDI-2

Observed Band(KD)：50kD

Background： GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

Function：function:Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.,similarity:Belongs to the Rab GDI family.,tissue specificity:Ubiquitous.,

Subcellular Location：Cytoplasm . Membrane ; Peripheral membrane protein .

Expression：Ubiquitous.