Target：GDF-7

Fields：Cytokine-cytokine receptor interaction;TGF-beta signaling pathway;Axon guidance;Hippo signaling pathway

Gene Name：GDF7

Protein Name：Growth/differentiation factor 7

Human Gene Id：151449

Human Swiss Prot No：Q7Z4P5

Mouse Gene Id：238057

Mouse Swiss Prot No：P43029

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370

Specificity：GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GDF7;Growth/differentiation factor 7;GDF-7

Observed Band(KD)：47kD

Background： This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],

Function：function:May play an active role in the motor area of the primate neocortex.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,

Subcellular Location：Secreted .

Expression： Testis,