Target：GDF-3

Fields：Cytokine-cytokine receptor interaction

Gene Name：GDF3

Protein Name：Growth/differentiation factor 3

Human Gene Id：9573

Human Swiss Prot No：Q9NR23

Mouse Gene Id：14562

Mouse Swiss Prot No：Q07104

Immunogen：Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

Specificity：GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GDF3;Growth/differentiation factor 3;GDF-3

Observed Band(KD)：41kD

Background： This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

Function：online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,

Subcellular Location：Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .

Expression： Kidney,