Target：EF1D

Gene Name：EEF1D EF1D

Protein Name：Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4)

Human Gene Id：1936

Human Swiss Prot No：P29692

Mouse Swiss Prot No：P57776

Rat Swiss Prot No：Q68FR9

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：EF1D Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：30kD

Background：eukaryotic translation elongation factor 1 delta(EEF1D) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010],

Function：function:EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the EF-1-beta/EF-1-delta family.,subunit:EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.,

Subcellular Location：[Isoform 2]: Nucleus .

Expression：Isoform 2 is specifically expressed in brain, cerebellum and testis.