Target：EDG-5

Fields：Sphingolipid signaling pathway;Neuroactive ligand-receptor interaction

Gene Name：S1PR2

Protein Name：Sphingosine 1-phosphate receptor 2

Human Gene Id：9294

Human Swiss Prot No：O95136

Mouse Gene Id：14739

Mouse Swiss Prot No：P52592

Rat Gene Id：29415

Rat Swiss Prot No：P47752

Immunogen：The antiserum was produced against synthesized peptide derived from human EDG5. AA range:261-310

Specificity：EDG-5 Polyclonal Antibody detects endogenous levels of EDG-5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：S1PR2;EDG5;Sphingosine 1-phosphate receptor 2;S1P receptor 2;S1P2;Endothelial differentiation G-protein coupled receptor 5;Sphingosine 1-phosphate receptor Edg-5;S1P receptor Edg-5

Observed Band(KD)：39kD

Background： This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016],

Function：function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression： Fetal brain,