Target：ECP

Fields：Asthma

Gene Name：RNASE3

Protein Name：Eosinophil cationic protein

Human Gene Id：6037

Human Swiss Prot No：P12724

Immunogen：The antiserum was produced against synthesized peptide derived from human ECP. AA range:102-151

Specificity：ECP Polyclonal Antibody detects endogenous levels of ECP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RNASE3;ECP;RNS3;Eosinophil cationic protein;ECP;Ribonuclease 3;RNase 3

Observed Band(KD)：18kD

Background： The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],

Function：disease:Induces the neurotoxic effect known as the Gordon phenomenon.,function:Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.,similarity:Belongs to the pancreatic ribonuclease family.,subcellular location:Matrix of eosinophil's large specific granule.,

Subcellular Location：Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.

Expression： Colon,Fetal liver,Peripheral blood granulocyte,