Target：DNA pol ε B

Fields：DNA replication;Base excision repair;Nucleotide excision repair

Gene Name：POLE2

Protein Name：DNA polymerase epsilon subunit 2

Human Gene Id：5427

Human Swiss Prot No：P56282

Mouse Swiss Prot No：O54956

Immunogen：Synthesized peptide derived from the Internal region of human DNA pol ε B.

Specificity：DNA pol ε B Polyclonal Antibody detects endogenous levels of DNA pol ε B protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：POLE2;DPE2;DNA polymerase epsilon subunit 2;DNA polymerase II subunit 2;DNA polymerase epsilon subunit B

Observed Band(KD)：59kD

Background：catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,function:Participates in DNA repair and in chromosomal DNA replication.,miscellaneous:In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.,similarity:Belongs to the DNA polymerase epsilon subunit B family.,subunit:Consists of four subunits: POLE, POLE2, POLE3 and POLE4.,

Function：catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,function:Participates in DNA repair and in chromosomal DNA replication.,miscellaneous:In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.,similarity:Belongs to the DNA polymerase epsilon subunit B family.,subunit:Consists of four subunits: POLE, POLE2, POLE3 and POLE4.,

Subcellular Location：Nucleus.

Expression： T cells,