Target:DKKL1
Gene Name:DKKL1 SGY1 UNQ735/PRO1429
Protein Name:Dickkopf-like protein 1 (Cancer/testis antigen 34) (CT34) (Protein soggy-1) (SGY-1)
Human Gene Id:27120
Human Swiss Prot No:Q9UK85
Mouse Swiss Prot No:Q9QZL9
Immunogen:Synthesized peptide derived from human protein . at AA range: 50-130
Specificity:DKKL1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):26kD
Background: The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010],
Function:PTM:N-glycosylated.,similarity:To the N-terminal section of DKK-3.,
Subcellular Location:Secreted . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized specifically to the crescent shaped acrosome at the apex of the sperm head. .
Expression:More highly expressed in adult testis than in fetal testis. Exclusively expressed in the testis (at protein level). Intense expression in stages II, III and IV of spermatogenesis, whereas expression is lower in stage I.