Target：Dkk-3

Gene Name：DKK3

Protein Name：Dickkopf-related protein 3

Human Gene Id：27122

Human Swiss Prot No：Q9UBP4

Mouse Gene Id：50781

Mouse Swiss Prot No：Q9QUN9

Immunogen：The antiserum was produced against synthesized peptide derived from human DKK3. AA range:111-160

Specificity：Dkk-3 Polyclonal Antibody detects endogenous levels of Dkk-3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DKK3;REIC;Dickkopf-related protein 3;Dickkopf-3;Dkk-3;hDkk-3

Observed Band(KD)：45kD

Background： This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

Function：function:Inhibitor of Wnt signaling pathway .,PTM:N-glycosylated.,similarity:Belongs to the dickkopf family.,tissue specificity:Highest expression in heart, brain, and spinal cord.,

Subcellular Location：Secreted.

Expression：Highest expression in heart, brain, and spinal cord.