Target:DHRS2
Gene Name:DHRS2
Protein Name:Dehydrogenase/reductase SDR family member 2
Human Gene Id:10202
Human Swiss Prot No:Q13268
Immunogen:The antiserum was produced against synthesized peptide derived from human DHRS2. AA range:111-160
Specificity:DHRS2 Polyclonal Antibody detects endogenous levels of DHRS2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:DHRS2;Dehydrogenase/reductase SDR family member 2;Dicarbonyl reductase HEP27;Protein D
Observed Band(KD):27kD
Background:function:May inhibit cell replication either by catalyzing the oxidation of estrogen and androgen or by converting cortisone in cortisol.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
Function:function:May inhibit cell replication either by catalyzing the oxidation of estrogen and androgen or by converting cortisone in cortisol.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
Subcellular Location:Mitochondrion matrix. Nucleus. A minor fraction of the protein is translocated from the mitochondria to the nucleus, after cleavage of the targeting signal.
Expression:Widely expressed, with highest levels in liver and kidney, followed by heart, spleen, skeletal muscle and placenta. In hemopoietic cells, expressed in dendritic cells, but not in monocytes, macrophages, granulocytes, nor in B and T lymphocytes.