Target：DEST

Gene Name：DSTN ACTDP DSN

Protein Name：Destrin (Actin-depolymerizing factor) (ADF)

Human Gene Id：11034

Human Swiss Prot No：P60981

Mouse Swiss Prot No：Q9R0P5

Rat Swiss Prot No：Q7M0E3

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：DEST Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：18kD

Background： The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Function：function:Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.,similarity:Belongs to the actin-binding proteins ADF family.,similarity:Contains 1 ADF-H domain.,tissue specificity:Widely distributed in various tissues.,

Subcellular Location：actin cytoskeleton,cortical actin cytoskeleton,extracellular exosome,

Expression：Widely distributed in various tissues.