Target:DBC1
Gene Name:KIAA1967
Protein Name:DBIRD complex subunit KIAA1967
Human Gene Id:57805
Human Swiss Prot No:Q8N163
Mouse Swiss Prot No:Q8VDP4
Immunogen:The antiserum was produced against synthesized peptide derived from human KIAA1967. AA range:431-480
Specificity:DBC-1 Polyclonal Antibody detects endogenous levels of DBC-1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:KIAA1967;DBC1;DBIRD complex subunit KIAA1967;Deleted in breast cancer gene 1 protein;DBC-1;DBC.1;p30 DBC
Observed Band(KD):102kD
Background:tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
Function:tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
Subcellular Location:Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
Expression:Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.