Target:CYP4F11
Gene Name:CYP4F11
Protein Name:Cytochrome P450 4F11
Human Gene Id:57834
Human Swiss Prot No:Q9HBI6
Immunogen:The antiserum was produced against synthesized peptide derived from human Cytochrome P450 4F11. AA range:341-390
Specificity:CYP4F11 Polyclonal Antibody detects endogenous levels of CYP4F11 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CYP4F11;Cytochrome P450 4F11;CYPIVF11
Observed Band(KD):60kD
Background:cytochrome P450 family 4 subfamily F member 11(CYP4F11) Homo sapiens This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Function:catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.,
Subcellular Location:Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
Expression:Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.