Target：GBP3

Fields：NOD-like receptor signaling pathway

Gene Name：GBP3

Protein Name：Guanylate-binding protein 3

Human Gene Id：2635

Human Swiss Prot No：Q9H0R5

Immunogen：The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530

Specificity：GBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GBP3;Guanylate-binding protein 3;GTP-binding protein 3;GBP-3;Guanine nucleotide-binding protein 3

Observed Band(KD)：64kD

Background： This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],

Function：function:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,

Subcellular Location：Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .

Expression： Brain,Prostate,