Target:GATA-5
Gene Name:GATA5
Protein Name:Transcription factor GATA-5
Human Gene Id:140628
Human Swiss Prot No:Q9BWX5
Mouse Gene Id:14464
Mouse Swiss Prot No:P97489
Immunogen:The antiserum was produced against synthesized peptide derived from human GATA-5. AA range:244-293
Specificity:GATA-5 Polyclonal Antibody detects endogenous levels of GATA-5 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GATA5;Transcription factor GATA-5;GATA-binding factor 5
Observed Band(KD):45kD
Background: The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008],
Function:function:Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity.,similarity:Contains 2 GATA-type zinc fingers.,
Subcellular Location:Nucleus .
Expression: Uterus,