Target:CTDSP1
Gene Name:CTDSP1
Protein Name:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Human Gene Id:58190
Human Swiss Prot No:Q9GZU7
Mouse Gene Id:227292
Mouse Swiss Prot No:P58466
Immunogen:The antiserum was produced against synthesized peptide derived from human CTDSP1. AA range:1-50
Specificity:CTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CTDSP1;NIF3;NLIIF;SCP1;Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1;Nuclear LIM interactor-interacting factor 3;NLI-IF;NLI-interacting factor 3;Small C-terminal domain phosphatase 1;SCP1;Small CTD ph
Observed Band(KD):30kD
Background:CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],
Function:catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,similarity:Contains 1 FCP1 homology domain.,subunit:May interact with LDB1 .,tissue specificity:Ubiquitously expressed, with highest expression in spleen, lung and placenta.,
Subcellular Location:Nucleus . Colocalizes with RNA polymerase II.
Expression:Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.