Target：CTACK

Fields：Cytokine-cytokine receptor interaction;Viral protein interaction with cytokine and cytokine receptor;Chemokine signaling pathway

Gene Name：CCL27

Protein Name：C-C motif chemokine 27

Human Gene Id：10850

Human Swiss Prot No：Q9Y4X3

Mouse Gene Id：100039863

Mouse Swiss Prot No：Q9Z1X0

Immunogen：Synthesized peptide derived from C-C motif chemokine 27 at AA range: 51-100

Specificity：CTACK Polyclonal Antibody detects endogenous levels of CTACK protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CCL27;ILC;SCYA27;C-C motif chemokine 27;CC chemokine ILC;Cutaneous T-cell-attracting chemokine;CTACK;ESkine;IL-11 R-alpha-locus chemokine;Skinkine;Small-inducible cytokine A27

Observed Band(KD)：12kD

Background： This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014],

Function：function:Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.,online information:CCL27 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Testis, thymus, placenta, ovary and skin.,

Subcellular Location：Secreted .

Expression：Testis, thymus, placenta, ovary and skin.