Target:CsGalNAcT-2
Fields:Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate;Metabolic pathways
Gene Name:CSGALNACT2
Protein Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 2
Human Gene Id:55454
Human Swiss Prot No:Q8N6G5
Mouse Gene Id:78752
Mouse Swiss Prot No:Q8C1F4
Immunogen:The antiserum was produced against synthesized peptide derived from human CSGALNACT2. AA range:61-110
Specificity:CsGalNAcT-2 Polyclonal Antibody detects endogenous levels of CsGalNAcT-2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CSGALNACT2;CHGN2;GALNACT2;Chondroitin sulfate N-acetylgalactosaminyltransferase 2;Chondroitin beta-1;4-N-acetylgalactosaminyltransferase 2;Beta4GalNAcT-2;GalNAcT-2
Observed Band(KD):63kD
Background: This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome X. [provided by RefSeq, Feb 2016],
Function:catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl-(1->3)-D-galactosyl-proteoglycan = UDP + N-acetyl-D-galactosaminyl-(1->4)-beta-D-glucuronyl-(1->3)-beta-D-galactosylproteoglycan.,function:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains.,online information:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2,online information:GlycoGene database,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,tissue specificity:Ubiquitous.,
Subcellular Location:Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein .
Expression:Ubiquitous.