Target：CPA1

Fields：Pancreatic secretion;Protein digestion and absorption

Gene Name：CPA1

Protein Name：Carboxypeptidase A1

Human Gene Id：1357

Human Swiss Prot No：P15085

Mouse Swiss Prot No：Q7TPZ8

Immunogen：The antiserum was produced against synthesized peptide derived from human Carboxypeptidase A1. AA range:301-350

Specificity：CPA1 Polyclonal Antibody detects endogenous levels of CPA1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CPA1;CPA;Carboxypeptidase A1

Observed Band(KD)：47kD

Background： This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015],

Function：catalytic activity:Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,subunit:Monomer. May form a complex with proelastase 2.,

Subcellular Location：Secreted.

Expression： Pancreas,