Target:Gasdermin C
Gene Name:GSDMC
Protein Name:Gasdermin-C
Human Gene Id:56169
Human Swiss Prot No:Q9BYG8
Mouse Swiss Prot No:Q99NB5
Immunogen:The antiserum was produced against synthesized peptide derived from human GSDMC. AA range:109-158
Specificity:Gasdermin C Polyclonal Antibody detects endogenous levels of Gasdermin C protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GSDMC;MLZE;Gasdermin-C;Melanoma-derived leucine zipper-containing extranuclear factor
Observed Band(KD):55kD
Background:caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
Function:caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
Subcellular Location:[Gasdermin-C]: Cytoplasm, cytosol .; [Gasdermin-C, N-terminal]: Cell membrane ; Multi-pass membrane protein .
Expression:Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310).