Target：CP4FC

Gene Name：CYP4F12 UNQ568/PRO1129

Protein Name：Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)

Human Gene Id：66002

Human Swiss Prot No：Q9HCS2

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CP4FC Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：57kD

Background：cytochrome P450 family 4 subfamily F member 12(CYP4F12) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Function：catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:Catalyzes leukotriene B4 omega-hydroxylation and arachidonic acid omega-hydroxylation but with an activity much lower than that of CYP4F2. Catalyzes the hydroxylation of the antihistamine ebastine.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Expressed in small intestine, liver, colon and heart.,

Subcellular Location：Endoplasmic reticulum membrane . Microsome membrane .

Expression：Expressed in small intestine, liver, colon and heart.