Target:Contactin 2
Fields:Cell adhesion molecules
Gene Name:CNTN2
Protein Name:Contactin-2
Human Gene Id:6900
Human Swiss Prot No:Q02246
Mouse Gene Id:21367
Mouse Swiss Prot No:Q61330
Rat Gene Id:25356
Rat Swiss Prot No:P22063
Immunogen:The antiserum was produced against synthesized peptide derived from human CNTN2. AA range:111-160
Specificity:Contactin 2 Polyclonal Antibody detects endogenous levels of Contactin 2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CNTN2;AXT;TAG1;TAX1;Contactin-2;Axonal glycoprotein TAG-1;Axonin-1;Transient axonal glycoprotein 1;TAX-1
Observed Band(KD):120kD
Background: This gene encodes a member of the contactin family of proteins, part of the immunoglobulin superfamily of cell adhesion molecules. The encoded glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein plays a role in the proliferation, migration, and axon guidance of neurons of the developing cerebellum. A mutation in this gene may be associated with adult myoclonic epilepsy. [provided by RefSeq, Sep 2016],
Function:function:May play a role in the initial growth and guidance of axons. May be involved in cell adhesion.,similarity:Belongs to the immunoglobulin superfamily. Contactin family.,similarity:Contains 4 fibronectin type-III domains.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.,
Subcellular Location:Cell membrane; Lipid-anchor, GPI-anchor. Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
Expression: Amygdala,Brain,Placenta,Plasma,