Target：Connexin-45

Gene Name：GJC1

Protein Name：Gap junction gamma-1 protein

Human Gene Id：10052

Human Swiss Prot No：P36383

Mouse Gene Id：14615

Mouse Swiss Prot No：P28229

Rat Gene Id：266706

Rat Swiss Prot No：A4GG66

Immunogen：The antiserum was produced against synthesized peptide derived from human GJC1. AA range:231-280

Specificity：Connexin 45 Polyclonal Antibody detects endogenous levels of Connexin 45 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GJC1;GJA7;Gap junction gamma-1 protein;Connexin-45;Cx45;Gap junction alpha-7 protein

Observed Band(KD)：45kD

Background： This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],

Function：function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins.,

Subcellular Location：Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Expression： Testis,Uterus,