Target:Connexin 37
Gene Name:GJA4
Protein Name:Gap junction alpha-4 protein
Human Gene Id:2701
Human Swiss Prot No:P35212
Mouse Gene Id:14612
Mouse Swiss Prot No:P28235
Rat Gene Id:25655
Rat Swiss Prot No:Q03190
Immunogen:The antiserum was produced against synthesized peptide derived from human GJA4. AA range:81-130
Specificity:Connexin 37 Polyclonal Antibody detects endogenous levels of Connexin 37 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GJA4;Gap junction alpha-4 protein;Connexin-37;Cx37
Observed Band(KD):37kD
Background: This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008],
Function:function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.,
Subcellular Location:Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Expression:Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.