Target：Connexin 25

Gene Name：GJB7

Protein Name：Gap junction beta-7 protein

Human Gene Id：375519

Human Swiss Prot No：Q6PEY0

Immunogen：The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70

Specificity：Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GJB7;CX25;Gap junction beta-7 protein;Connexin-25;Cx25

Observed Band(KD)：24kD

Background： Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],

Function：function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .

Expression：Weakly expressed in placenta.