Target：COL14A1

Fields：Protein digestion and absorption

Gene Name：COL14A1

Protein Name：Collagen alpha-1(XIV) chain

Human Gene Id：7373

Human Swiss Prot No：Q05707

Mouse Swiss Prot No：Q80X19

Immunogen：The antiserum was produced against synthesized peptide derived from human N-ternal Collagen XIV alpha1. AA range:71-120

Specificity：COL14A1 Polyclonal Antibody detects endogenous levels of COL14A1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：COL14A1;UND;Collagen alpha-1(XIV) chain;Undulin

Molecular Weight(Da)：194kD

Background： This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis. [provided by RefSeq, Jan 2013],

Function：function:Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.,PTM:Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates.,PTM:May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:

Subcellular Location：Secreted, extracellular space, extracellular matrix .

Expression： Brain,Liver,Muscle,PNS,Testis,