Target：COE3

Gene Name：EBF3 COE3

Protein Name：Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2)

Human Gene Id：253738

Human Swiss Prot No：Q9H4W6

Mouse Swiss Prot No：O08791

Immunogen：Synthesized peptide derived from human protein . at AA range: 50-130

Specificity：COE3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：65kD

Background： This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011],

Function：function:Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.,similarity:Belongs to the COE family.,similarity:Contains 1 IPT/TIG domain.,subunit:Forms either a homodimer or a heterodimer with a related family member.,tissue specificity:Expressed in brain.,

Subcellular Location：Nucleus .

Expression：Expressed in brain.