Target：GALR1

Fields：Neuroactive ligand-receptor interaction

Gene Name：GALR1

Protein Name：Galanin receptor type 1

Human Gene Id：2587

Human Swiss Prot No：P47211

Mouse Gene Id：14427

Mouse Swiss Prot No：P56479

Immunogen：The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210

Specificity：GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GALR1;GALNR;GALNR1;Galanin receptor type 1;GAL1-R;GALR-1

Molecular Weight(Da)：39kD

Background： The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],

Function：function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression： Brain,Melanoma,Small intestine,