Target：KREM1

Gene Name：KREMEN1 KREMEN KRM1

Protein Name：Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)

Human Gene Id：83999

Human Swiss Prot No：Q96MU8

Mouse Swiss Prot No：Q99N43

Rat Swiss Prot No：Q924S4

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：KREM1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：52kD

Background： This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008],

Function：function:Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling.,similarity:Contains 1 CUB domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 WSC domain.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression： Eye,