Target：KCNKG

Gene Name：KCNK16 TALK1

Protein Name：Potassium channel subfamily K member 16 (2P domain potassium channel Talk-1) (TWIK-related alkaline pH-activated K(+) channel 1) (TALK-1)

Human Gene Id：83795

Human Swiss Prot No：Q96T55

Immunogen：Synthesized peptide derived from human protein . at AA range: 230-310

Specificity：KCNKG Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：33kD

Background：potassium two pore domain channel subfamily K member 16(KCNK16) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008],

Function：function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinine, quinidine, chloroform and halothane. Activated at alkaline pH.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Highly expressed in pancreas. Not detectable in the other tissues tested.,

Subcellular Location：Membrane; Multi-pass membrane protein.

Expression：Highly expressed in pancreas. Not detectable in the other tissues tested.