Target：K1H1

Fields：Estrogen signaling pathway;Staphylococcus aureus infection

Gene Name：KRT31 HHA1 HKA1 KRTHA1

Protein Name：Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)

Human Gene Id：3881

Human Swiss Prot No：Q15323

Mouse Swiss Prot No：Q61765

Immunogen：Synthesized peptide derived from human protein . at AA range: 10-90

Specificity：K1H1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：45kD

Background： The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008],

Function：miscellaneous:There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).,similarity:Belongs to the intermediate filament family.,tissue specificity:Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla.,

Subcellular Location：extracellular space,intermediate filament,extracellular exosome,

Expression：Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla.