Target:Jun D
Fields:MAPK signaling pathway;Osteoclast differentiation;IL-17 signaling pathway;Parathyroid hormone synthesis, secretion and action
Gene Name:JUND
Protein Name:Transcription factor jun-D
Human Gene Id:3727
Human Swiss Prot No:P17535
Mouse Gene Id:16478
Mouse Swiss Prot No:P15066
Rat Gene Id:24518
Rat Swiss Prot No:P52909
Immunogen:The antiserum was produced against synthesized peptide derived from human JunD. AA range:222-271
Specificity:Jun D Polyclonal Antibody detects endogenous levels of Jun D protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:JUND;Transcription factor jun-D
Observed Band(KD):38kD
Background: The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013],
Function:function:Binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer.,
Subcellular Location:Nucleus.
Expression: Epithelium,Spleen,