Target：GABARAP

Fields：FoxO signaling pathway;Autophagy - other;Mitophagy - animal;Autophagy - animal;NOD-like receptor signaling pathway;GABAergic synapse

Gene Name：GABARAPL2 FLC3A GEF2

Protein Name：GABARAP

Human Gene Id：11345

Human Swiss Prot No：P60520

Mouse Gene Id：93739

Mouse Swiss Prot No：P60521

Rat Swiss Prot No：P60522

Immunogen：Synthetic Peptide of GABARAP AA range: 26-75

Specificity：GABARAP Polyclonal Antibody detects endogenous levels of GABARAP

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000, ELISA 1:10000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GABA(A) receptor-associated protein-like 2

Observed Band(KD)：17kD

Background：function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 LC3 family.,subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1.,tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.,

Function：function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 LC3 family.,subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1.,tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.,

Subcellular Location：Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum membrane . Golgi apparatus .

Expression：Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.