Target：ITLN1

Gene Name：ITLN1 INTL ITLN LFR UNQ640/PRO1270

Protein Name：Intelectin-1 (ITLN-1) (Endothelial lectin HL-1) (Galactofuranose-binding lectin) (Intestinal lactoferrin receptor) (Omentin)

Human Gene Id：55600

Human Swiss Prot No：Q8WWA0

Immunogen：Synthesized peptide derived from human protein . at AA range: 110-190

Specificity：ITLN1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：34kD

Background：developmental stage:Found in fetal small intestine and thymus.,function:Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.,mass spectrometry: PubMed:17621593,PTM:N-glycosylated.,similarity:Contains 1 fibrinogen C-terminal domain.,subcellular location:Enriched in lipid rafts.,subunit:Homotrimer; disulfide-linked.,tissue specificity:Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.,

Function：developmental stage:Found in fetal small intestine and thymus.,function:Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.,mass spectrometry: PubMed:17621593,PTM:N-glycosylated.,similarity:Contains 1 fibrinogen C-terminal domain.,subcellular location:Enriched in lipid rafts.,subunit:Homotrimer; disulfide-linked.,tissue specificity:Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expre

Subcellular Location：Cell membrane ; Lipid-anchor, GPI-anchor . Secreted . Enriched in lipid rafts. .

Expression：Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level) (PubMed:16531507). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.