Target：IP6K2

Fields：Phosphatidylinositol signaling system

Gene Name：IP6K2

Protein Name：Inositol hexakisphosphate kinase 2

Human Gene Id：51447

Human Swiss Prot No：Q9UHH9

Mouse Gene Id：76500

Mouse Swiss Prot No：Q80V72

Rat Gene Id：59268

Rat Swiss Prot No：Q9R0U1

Immunogen：The antiserum was produced against synthesized peptide derived from human IP6K2. AA range:161-210

Specificity：IP6K2 Polyclonal Antibody detects endogenous levels of IP6K2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：IP6K2;IHPK2;TCCCIA00113;Inositol hexakisphosphate kinase 2;InsP6 kinase 2;P(i)-uptake stimulator;PiUS

Observed Band(KD)：49kD

Background： This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Function：catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family.,

Subcellular Location：Nucleus .

Expression： Caudate nucleus,Glial tumor,Leukemia,Lung,Skin,Uterus,