Target：Integrin β5

Fields：Phagosome;PI3K-Akt signaling pathway;Focal adhesion;ECM-receptor interaction;Regulation of actin cytoskeleton;Human papillomavirus infection;Proteoglycans in cancer;Hypertrophic cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy;Dilated cardiomyopathy

Gene Name：ITGB5

Protein Name：Integrin beta-5

Human Gene Id：3693

Human Swiss Prot No：P18084

Mouse Gene Id：16419

Mouse Swiss Prot No：O70309

Immunogen：The antiserum was produced against synthesized peptide derived from human Integrin beta5. AA range:721-770

Specificity：Integrin β5 Polyclonal Antibody detects endogenous levels of Integrin β5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ITGB5;Integrin beta-5

Observed Band(KD)：88kD

Background：function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.,

Function：function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.,

Subcellular Location：Membrane; Single-pass type I membrane protein.

Expression： Brain,Kidney,Thymic epithelium,