Target：IL-32

Fields：Cytokine-cytokine receptor interaction

Gene Name：IL32

Protein Name：Interleukin-32

Human Gene Id：9235

Human Swiss Prot No：P24001

Immunogen：The antiserum was produced against synthesized peptide derived from human IL-32. AA range:177-226

Specificity：IL-32 Polyclonal Antibody detects endogenous levels of IL-32 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：IL32;NK4;TAIF;Interleukin-32;IL-32;Natural killer cells protein 4;Tumor necrosis factor alpha-inducing factor

Observed Band(KD)：26kD

Background： This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Function：caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.,induction:Expression increased after activation of T-cells by mitogens or activation of NK cells by IL-2.,tissue specificity:Selectively expressed in lymphocytes. Expression more prominent in immunce cells than in non-immune cells.,

Subcellular Location：Secreted .

Expression：Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells.