Target：IL-29

Fields：Cytokine-cytokine receptor interaction;JAK-STAT signaling pathway

Gene Name：IL29

Protein Name：Interleukin-29

Human Gene Id：282618

Human Swiss Prot No：Q8IU54

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human IL29. AA range:121-170

Specificity：IL-29 Polyclonal Antibody detects endogenous levels of IL-29 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：IL29;IFNL1;ZCYTO21;Interleukin-29;IL-29;Cytokine Zcyto21;Interferon lambda-1;IFN-lambda-1

Observed Band(KD)：21kD

Background： This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008],

Function：function:Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,induction:By viral infections or double stranded RNA.,online information:Interleukin-29 entry,similarity:Belongs to the IL-28/IL-29 family.,

Subcellular Location：Secreted.