Target:FLRT3
Gene Name:FLRT3 KIAA1469 UNQ856/PRO1865
Protein Name:Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)
Human Gene Id:23767
Human Swiss Prot No:Q9NZU0
Rat Swiss Prot No:B1H234
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:FLRT3 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):71kD
Background:fibronectin leucine rich transmembrane protein 3(FLRT3) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010],
Function:function:May have a function in cell adhesion and/or receptor signaling.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.,
Subcellular Location:Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cell junction, focal adhesion . Secreted . Cell projection, axon . Cell projection, growth cone membrane . Detected on dendritic punctae that colocalize in part with glutamaergic synapses, but not with GABAergic synapses. Proteolytic cleavage in the juxtamembrane region gives rise to a shedded ectodomain. .
Expression:Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.