Target：FKBPL

Gene Name：FKBPL

Protein Name：FK506-binding protein-like

Human Gene Id：63943

Human Swiss Prot No：Q9UIM3

Mouse Gene Id：56299

Mouse Swiss Prot No：O35450

Rat Gene Id：406168

Rat Swiss Prot No：Q6MG81

Immunogen：The antiserum was produced against synthesized peptide derived from human FKBPL. AA range:251-300

Specificity：FKBPL Polyclonal Antibody detects endogenous levels of FKBPL protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FKBPL;DIR1;NG7;FK506-binding protein-like;WAF-1/CIP1 stabilizing protein 39;WISp39

Observed Band(KD)：38kD

Background： The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008],

Function：function:May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 TPR repeats.,subunit:Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.,tissue specificity:Ubiquitously expressed with higher levels in testis.,

Subcellular Location：endoplasmic reticulum membrane,cytosol,

Expression：Ubiquitously expressed with higher levels in testis.