Target：Fibulin-2

Gene Name：FBLN2

Protein Name：Fibulin-2

Human Gene Id：2199

Human Swiss Prot No：P98095

Mouse Swiss Prot No：P37889

Immunogen：The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290

Specificity：Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FBLN2;Fibulin-2;FIBL-2

Observed Band(KD)：130kD

Background： This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Function：developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,

Subcellular Location：Secreted, extracellular space, extracellular matrix.

Expression：Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.