Target：FHR1

Fields：Complement and coagulation cascades

Gene Name：CFHR1 CFHL CFHL1 CFHL1P CFHR1P FHR1 HFL1 HFL2

Protein Name：Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36)

Human Gene Id：3078

Human Swiss Prot No：Q03591

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：FHR1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：36kD

Background： This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009],

Function：function:Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.,PTM:N-glycosylated. Two forms are observed; one with a single side chain and the other with two.,similarity:Contains 5 Sushi (CCP/SCR) domains.,tissue specificity:Expressed by the liver and secreted in plasma.,

Subcellular Location：Secreted.

Expression：Expressed by the liver and secreted in plasma.